The latest from NuvOx

asoconstriction in cerebral pial arterioles of healthy rats.

Rats given DDFPe see a 72% reduction in myocardial infarct volume at 24 hours.

Intravenous DDFPe decreases ischemic stroke infarct volumes. Rapid development is warranted.

Intravenous DDFPe in an animal model decreases infarct volumes and protects brain tissue from ischemia justifying further investigation.

19 pigs with depressed arterial oxygen tensions had DDFPe administered. DDFPe increased arterial, venous, and muscle oxygen tensions.

DDFPe improves the efficiency of oxygen exchange between blood and tissue. Link to publication

US Army experiments concluding that DDFPe is a better resuscitation fluid then Hextend.

DDFPe absorbs more oxygen than other perfluorocarbon emulsions in-vitro.

DDFPe treated rats see 100% survival at hemoglobin levels lower than what is fatal in 100% of controls.

Pigs given 50% blood loss see 20% survival in controls (n=5) and 100% survival in those given DDFPe (n=5).

Air breathing pigs are given severe bleeding and either placebo or DDFPe. 0% of placebo animals survive. 100% of DDFPe animals survive.

DDFP plus carbogen appears to completely reverse the hypoxic cell radioresistance in this rat tumor model.

US Army Studies concluding that DDFPe holds promise in combat casualty care, even when oxygen is not readily available.

In this human PK study, DDFPe was given to 24 volunteers. DDFPe blood concentration decreases quickly. The drug is exhaled unmetabolized.

Pigs had airways blocked and were given 100% O2 to breathe. DDFPe infusions increase arterial oxygen tensions within minutes.

DDFPe increases arterial oxygen tension and muscle oxygen tension in pigs with pulmonary shunt.

In pigs that haid airflow in the lungs blocked by steel beads, administering DDFPe increased blood and muscle oxygen levels.