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Treatment of Swine Closed Head Injury with Perfluorocarbon
NanO2 may assist in mitigating secondary cellular brain damage after traumatic brain injury.


Welcoming the New Kid on the Block; A Phase IIb Study of DDFPe in Large Vessel Strokes
The design for an efficient Phase IIb clinical trial in stroke to test DDFPe in patients with Large Vessel Occlusions.


A Phase Ib/II clinical trial of DDFPe as a radiosensitizer in glioblastoma
Although small, this trial shows that DDFPe used as a radiosensitizer appears to be safe and may provide some survival benefit.


Dodecafluoropentane Emulsion in Acute Ischemic Stroke: A Phase Ib/II Trial
This randomized, placebo-controlled, double-blind, dose-escalation clinical trial in acute ischemic stroke patients was designed to...


Imaging assessment of cardioprotection mediated by DDFPe administered during myocardial infarction
DDFPe treatment in rats with myocardial infarction was associated by significantly reduced ischemia-reperfusion injury.


NuvOx Pharma’s NanO2 Shows Positive Results in Phase Ib/II Stroke Trial
Positive results of NuvOx Pharma’s NanO2 (DDFPe) in the treatment of stroke have been published at the International Stroke Conference. A...


In vitro model to compare the oxygen offloading behaviour of dodecafluoropentane emulsion (DDFPe)
DDFPe efficiently offloads oxygen to hypoxic environments. Link to publication


DDFPe as a Resuscitation Fluid for Hemorrhagic Shock and Traumatic Brain Injury: A Review
Animal studies, for both hemorrhagic shock and TBI, show promising effects of DDFPe as a resuscitation fluid.


DDFPe reduced secondary brain injury in a Swine Model of Traumatic Brain Injury
In this swine model of TBI, administration of DDFPe resulted in lower injury scores for
spongiosis and ischemic neurons.
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